CA2 Back

carbonic anhydrase II

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NCBI Description of CA2

CA2 is one of several (at least 7) isozymes of carbonic anhydrase. Carbonic anhydrase catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis.

Community Annotation of CA2 Add / Edit CA2: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


CA2 is highly significantly mutated in
CA2 is significantly mutated in
CA2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for CA2