C9 Back

complement component 9

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of C9

This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency.

Community Annotation of C9 Add / Edit C9: Annotations

No community annotations yet for C9.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

C9 is highly significantly mutated in
(none)
C9 is significantly mutated in
(none)
C9 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for C9