C8B Back

complement component 8, beta polypeptide

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NCBI Description of C8B
C8 beta is one of the three subunits that comprise the component 8 (C8) of the complement system. C8 participates in the formation of Membrane Attack Complex that results in the lysis of cells. Patients with C8B deficiency are prone to bacteria infection.

Community Annotation of C8B Add / Edit C8B: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

C8B is highly significantly mutated in
(none)
C8B is significantly mutated in
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C8B is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for C8B