C3 Back

complement component 3

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NCBI Description of C3
Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacterial infection.

Community Annotation of C3 Add / Edit C3: Annotations

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Sort mutations by: Tumor type  Mutation type  Position  
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

C3 is highly significantly mutated in
(none)
C3 is significantly mutated in
(none)
C3 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for C3