C1QBP Back

complement component 1, q subcomponent binding protein

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NCBI Description of C1QBP

The human complement subcomponent C1q associates with C1r and C1s in order to yield the first component of the serum complement system. The protein encoded by this gene is known to bind to the globular heads of C1q molecules and inhibit C1 activation. This protein has also been identified as the p32 subunit of pre-mRNA splicing factor SF2, as well as a hyaluronic acid-binding protein.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

C1QBP is highly significantly mutated in
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C1QBP is significantly mutated in
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C1QBP is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for C1QBP