BUB3 Back

BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast)

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NCBI Description of BUB3

This gene encodes a protein involved in spindle checkpoint function. The encoded protein contains four WD repeat domains and has sequence similarity with the yeast BUB3 protein. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


BUB3 is highly significantly mutated in
BUB3 is significantly mutated in
BUB3 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for BUB3