NCBI Description of BUB1B
|This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.|
Community Annotation of BUB1B Add / Edit BUB1B: Annotations
No community annotations yet for BUB1B.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.