BUB1 Back

BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast)

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NCBI Description of BUB1
This gene encodes a kinase involved in spindle checkpoint function. The kinase functions in part by phosphorylating a member of the miotic checkpoint complex and activating the spindle checkpoint. Mutations in this gene have been associated with aneuploidy and several forms of cancer.

Community Annotation of BUB1 Add / Edit BUB1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

BUB1 is highly significantly mutated in
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BUB1 is significantly mutated in
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BUB1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for BUB1