BTLA Back

B and T lymphocyte associated

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NCBI Description of BTLA
This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis.

Community Annotation of BTLA Add / Edit BTLA: Annotations

No community annotations yet for BTLA.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

BTLA is highly significantly mutated in
(none)
BTLA is significantly mutated in
(none)
BTLA is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for BTLA