B and T lymphocyte associated

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of BTLA

This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis.

Community Annotation of BTLA Add / Edit BTLA: Annotations

No community annotations yet for BTLA.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


BTLA is highly significantly mutated in
BTLA is significantly mutated in
BTLA is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for BTLA