BTBD2 Back

BTB (POZ) domain containing 2

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NCBI Description of BTBD2
The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

BTBD2 is highly significantly mutated in
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BTBD2 is significantly mutated in
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BTBD2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for BTBD2