BRDT Back

bromodomain, testis-specific

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NCBI Description of BRDT

BRDT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues), characteristic of proteins that undergo rapid intracellular degradation. The bromodomain is found in proteins that regulate transcription. Several transcript variants encoding multiple isoforms have been found for this gene.

Community Annotation of BRDT Add / Edit BRDT: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

BRDT is highly significantly mutated in
(none)
BRDT is significantly mutated in
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BRDT is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for BRDT