BNIP2 Back

BCL2/adenovirus E1B 19kDa interacting protein 2

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NCBI Description of BNIP2
This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. Sequence Note: The translation start codon selected for this RefSeq is conserved in human and Rhesus macaque. A possible downstream start codon, which shows better cross-species conservation, would shorten the protein by 121 aa. The shorter protein is described in the literature, including PMID:7954800. No experimental evidence exists to show which start codon is used in vivo.

Community Annotation of BNIP2 Add / Edit BNIP2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

BNIP2 is highly significantly mutated in
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BNIP2 is significantly mutated in
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BNIP2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for BNIP2