BNIP1 Back

BCL2/adenovirus E1B 19kDa interacting protein 1

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NCBI Description of BNIP1
This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. In addition, this protein is involved in vesicle transport into the endoplasmic reticulum. Alternative splicing of this gene results in four protein products with identical N- and C-termini.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

BNIP1 is highly significantly mutated in
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BNIP1 is significantly mutated in
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BNIP1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for BNIP1