BMPER Back

BMP binding endothelial regulator

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NCBI Description of BMPER

This gene encodes a secreted protein that interacts with, and inhibits bone morphogenetic protein (BMP) function. It has been shown to inhibit BMP2- and BMP4-dependent osteoblast differentiation and BMP-dependent differentiation of the chondrogenic cells. Mutations in this gene are associated with a lethal skeletal disorder, diaphanospondylodysostosis.

Community Annotation of BMPER Add / Edit BMPER: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

BMPER is highly significantly mutated in
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BMPER is significantly mutated in
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BMPER is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for BMPER