BMP15 Back

bone morphogenetic protein 15

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NCBI Description of BMP15

The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The transforming growth factor-beta superfamily includes large families of growth and differentiation factors. It is thought that this protein may be involved in oocyte maturation and follicular development as a homodimer or by forming heterodimers with a related protein, Gdf9. Defects in this gene are the cause of ovarian dysgenesis 2.

Community Annotation of BMP15 Add / Edit BMP15: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

BMP15 is highly significantly mutated in
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BMP15 is significantly mutated in
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BMP15 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for BMP15