BIRC6 Back

baculoviral IAP repeat-containing 6 (apollon)

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NCBI Description of BIRC6
This gene encodes a protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. This protein inhibits apoptosis by facilitating the degradation of apoptotic proteins by ubiquitination. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

BIRC6 is highly significantly mutated in
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BIRC6 is significantly mutated in
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BIRC6 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for BIRC6