BICD2 Back

bicaudal D homolog 2 (Drosophila)

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NCBI Description of BICD2
This gene is one of two human homologs of Drosophila bicaudal-D and a member of the Bicoid family. It has been implicated in dynein-mediated, minus end-directed motility along microtubules. It has also been reported to be a phosphorylation target of NIMA related kinase 8. Two alternative splice variants have been described.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

BICD2 is highly significantly mutated in
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BICD2 is significantly mutated in
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BICD2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for BICD2