BCMO1 Back

beta-carotene 15,15'-monooxygenase 1

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NCBI Description of BCMO1
Vitamin A metabolism is important for vital processes such as vision, embryonic development, cell differentiation, and membrane and skin protection. The protein encoded by this gene is a key enzyme in beta-carotene metabolism to vitamin A. It catalyzes the oxidative cleavage of beta,beta-carotene into two retinal molecules.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

BCMO1 is highly significantly mutated in
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BCMO1 is significantly mutated in
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BCMO1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for BCMO1