BCL7B Back

B-cell CLL/lymphoma 7B

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NCBI Description of BCL7B

This gene encodes a member of the BCL7 family including BCL7A, BCL7B and BCL7C proteins. This member is BCL7B, which contains a region that is highly similar to the N-terminal segment of BCL7A or BCL7C proteins. The BCL7A protein is encoded by the gene known to be directly involved in a three-way gene translocation in a Burkitt lymphoma cell line. This gene is located at a chromosomal region commonly deleted in Williams syndrome. This gene is highly conserved from C. elegans to human. Multiple alternatively spliced transcript variants have been found for this gene.

Community Annotation of BCL7B Add / Edit BCL7B: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


BCL7B is highly significantly mutated in
BCL7B is significantly mutated in
BCL7B is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for BCL7B