BCKDK Back

branched chain ketoacid dehydrogenase kinase

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NCBI Description of BCKDK
The branched-chain alpha-ketoacid dehydrogenase complex (BCKD) is an important regulator of the valine, leucine, and isoleucine catabolic pathways. The protein encoded by this gene is found in the mitochondrion, where it phosphorylates and inactivates BCKD. Several transcript variants encoding different isoforms have been found for this gene.

Community Annotation of BCKDK Add / Edit BCKDK: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

BCKDK is highly significantly mutated in
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BCKDK is significantly mutated in
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BCKDK is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for BCKDK