BCAN Back

brevican

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NCBI Description of BCAN
This gene encodes a member of the lectican family of chondroitin sulfate proteoglycans that is specifically expressed in the central nervous system. This protein is developmentally regulated and may function in the formation of the brain extracellular matrix. This protein is highly expressed in gliomas and may promote the growth and cell motility of brain tumor cells. Alternate splicing results in multiple transcript variants.

Community Annotation of BCAN Add / Edit BCAN: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

BCAN is highly significantly mutated in
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BCAN is significantly mutated in
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BCAN is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for BCAN