B3GNT5 Back

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5

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NCBI Description of B3GNT5
This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II membrane protein. It exhibits strong activity to transfer GlcNAc to glycolipid substrates and is identified as the most likely candidate for lactotriaosylceramide synthase. This enzyme is essential for the expression of Lewis X epitopes on glycolipids.

Community Annotation of B3GNT5 Add / Edit B3GNT5: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

B3GNT5 is highly significantly mutated in
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B3GNT5 is significantly mutated in
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B3GNT5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for B3GNT5