AWAT2 Back

acyl-CoA wax alcohol acyltransferase 2

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NCBI Description of AWAT2

This gene encodes an enzyme belonging to the diacylglycerol acyltransferase family. This enzyme produces wax esters by the esterification of long chain (or wax) alcohols with acyl-CoA-derived fatty acids. It functions in lipid metabolism in the skin, mostly in undifferentiated peripheral sebocytes. This enzyme may also have acyl-CoA:retinol acyltransferase activities, where it catalyzes the synthesis of diacylglycerols and retinyl esters.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

AWAT2 is highly significantly mutated in
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AWAT2 is significantly mutated in
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AWAT2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for AWAT2