AURKB Back

aurora kinase B

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NCBI Description of AURKB

This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding different isoforms have been found for this gene.

Community Annotation of AURKB Add / Edit AURKB: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

AURKB is highly significantly mutated in
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AURKB is significantly mutated in
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AURKB is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for AURKB