ATP8B3 Back

ATPase, class I, type 8B, member 3

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NCBI Description of ATP8B3

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to the other. This gene encodes member 3 of phospholipid-transporting ATPase 8B; other members of this protein family are located on chromosomes 1, 15 and 18. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of ATP8B3 Add / Edit ATP8B3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ATP8B3 is highly significantly mutated in
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ATP8B3 is significantly mutated in
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ATP8B3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ATP8B3