ATP5L Back

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit G

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of ATP5L
Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the g subunit of the Fo complex. Alternative splicing results in multiple transcript variants.

Community Annotation of ATP5L Add / Edit ATP5L: Annotations

No community annotations yet for ATP5L.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ATP5L is highly significantly mutated in
(none)
ATP5L is significantly mutated in
(none)
ATP5L is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ATP5L