ATP12A Back

ATPase, H+/K+ transporting, nongastric, alpha polypeptide

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NCBI Description of ATP12A
The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This gene encodes a catalytic subunit of the ouabain-sensitive H+/K+ -ATPase that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for potassium absorption in various tissues. Two transcript variants encoding different isoforms have been found for this gene.

Community Annotation of ATP12A Add / Edit ATP12A: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ATP12A is highly significantly mutated in
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ATP12A is significantly mutated in
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ATP12A is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ATP12A