NCBI Description of ATOX1
|This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome.|
Community Annotation of ATOX1 Add / Edit ATOX1: Annotations
No community annotations yet for ATOX1.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.