ATG12 Back

ATG12 autophagy related 12 homolog (S. cerevisiae)

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NCBI Description of ATG12
Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).[supplied by OMIM, Mar 2008].

Community Annotation of ATG12 Add / Edit ATG12: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ATG12 is highly significantly mutated in
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ATG12 is significantly mutated in
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ATG12 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ATG12