ATF3 Back

activating transcription factor 3

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NCBI Description of ATF3
This gene encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This gene is induced by a variety of signals, including many of those encountered by cancer cells, and is involved in the complex process of cellular stress response. Multiple transcript variants encoding different isoforms have been found for this gene. It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes.

Community Annotation of ATF3 Add / Edit ATF3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ATF3 is highly significantly mutated in
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ATF3 is significantly mutated in
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ATF3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ATF3