ATE1 Back

arginyltransferase 1

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NCBI Description of ATE1

This gene encodes an arginyltransferase, an enzyme that is involved in posttranslational conjugation of arginine to N-terminal aspartate or glutamate residues. Conjugation of arginine to the N-terminal aspartate or glutamate targets proteins for ubiquitin-dependent degradation. Alternative splicing results in two transcript variants encoding distinct isoforms.

Community Annotation of ATE1 Add / Edit ATE1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ATE1 is highly significantly mutated in
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ATE1 is significantly mutated in
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ATE1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ATE1