ASNA1 Back

arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)

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NCBI Description of ASNA1
This gene represents the human homolog of the bacterial arsA gene, encoding the arsenite-stimulated ATPase component of the arsenite transporter responsible for resistance to arsenicals. This protein is also a central component of a transmembrane domain (TMD) recognition complex (TRC) that is involved in the post-translational delivery of tail-anchored (TA) proteins from the cytosol to the endoplasmic reticulum (ER). It recognizes and selectively binds the TMD of TA proteins in the cytosol, and delivers them to the ER for insertion.

Community Annotation of ASNA1 Add / Edit ASNA1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ASNA1 is highly significantly mutated in
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ASNA1 is significantly mutated in
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ASNA1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ASNA1