ASB6 Back

ankyrin repeat and SOCS box-containing 6

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NCBI Description of ASB6
The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contain a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box, similar to the F-box, acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. Alternatively spliced transcript variants have been identified for this gene.

Community Annotation of ASB6 Add / Edit ASB6: Annotations

No community annotations yet for ASB6.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ASB6 is highly significantly mutated in
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ASB6 is significantly mutated in
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ASB6 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ASB6