ASB5 Back

ankyrin repeat and SOCS box-containing 5

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NCBI Description of ASB5

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.

Community Annotation of ASB5 Add / Edit ASB5: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


ASB5 is highly significantly mutated in
ASB5 is significantly mutated in
ASB5 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for ASB5