ASB3 Back

ankyrin repeat and SOCS box-containing 3

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NCBI Description of ASB3

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternatively spliced transcript variants have been described for this gene.

Community Annotation of ASB3 Add / Edit ASB3: Annotations

No community annotations yet for ASB3.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ASB3 is highly significantly mutated in
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ASB3 is significantly mutated in
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ASB3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ASB3