ASB14 Back

ankyrin repeat and SOCS box-containing 14

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NCBI Description of ASB14
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternative splicing results in multiple transcript variants encoding different isoforms.

Community Annotation of ASB14 Add / Edit ASB14: Annotations

No community annotations yet for ASB14.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ASB14 is highly significantly mutated in
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ASB14 is significantly mutated in
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ASB14 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ASB14