ASAP3 Back

ArfGAP with SH3 domain, ankyrin repeat and PH domain 3

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NCBI Description of ASAP3
This gene encodes a member of a subfamily of ADP-ribosylation factor(Arf) GTPase-activating proteins that contain additional ankyrin repeat and pleckstrin homology domains. The Arf GAP domain of this protein catalyzes the hydrolysis of GTP bound to Arf proteins. The encoded protein promotes cell differentiation and migration and has been implicated in cancer cell invasion. Alternative splicing results in multiple transcript variants.

Community Annotation of ASAP3 Add / Edit ASAP3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ASAP3 is highly significantly mutated in
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ASAP3 is significantly mutated in
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ASAP3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ASAP3