ARX Back

aristaless related homeobox

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NCBI Description of ARX
This gene is a homeobox-containing gene expressed during development. The expressed protein contains two conserved domains, a C-peptide (or aristaless domain) and the prd-like class homeobox domain. It is a member of the group-II aristaless-related protein family whose members are expressed primarily in the central and/or peripheral nervous system. This gene is thought to be involved in CNS development. Mutations in this gene cause X-linked mental retardation and epilepsy.

Community Annotation of ARX Add / Edit ARX: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ARX is highly significantly mutated in
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ARX is significantly mutated in
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ARX is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ARX