ARSG Back

arylsulfatase G

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of ARSG

The protein encoded by this gene belongs to the sulfatase enzyme family. Sulfatases hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This protein displays arylsulfatase activity at acidic pH, as is typical of lysosomal sulfatases, and has been shown to localize in the lysosomes. Alternatively spliced transcript variants have been found for this gene.

Community Annotation of ARSG Add / Edit ARSG: Annotations

No community annotations yet for ARSG.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ARSG is highly significantly mutated in
(none)
ARSG is significantly mutated in
(none)
ARSG is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ARSG