ARPP21 Back

cAMP-regulated phosphoprotein, 21kDa

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NCBI Description of ARPP21
This gene encodes a cAMP-regulated phosphoprotein. The encoded protein is enriched in the caudate nucleus and cerebellar cortex. A similar protein in mouse may be involved in regulating the effects of dopamine in the basal ganglia. Alternate splicing results in multiple transcript variants.

Community Annotation of ARPP21 Add / Edit ARPP21: Annotations

No community annotations yet for ARPP21.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ARPP21 is highly significantly mutated in
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ARPP21 is significantly mutated in
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ARPP21 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ARPP21