ARPC5 Back

actin related protein 2/3 complex, subunit 5, 16kDa

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NCBI Description of ARPC5
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p16 subunit, has yet to be determined. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene.

Community Annotation of ARPC5 Add / Edit ARPC5: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ARPC5 is highly significantly mutated in
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ARPC5 is significantly mutated in
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ARPC5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ARPC5