ARNTL Back

aryl hydrocarbon receptor nuclear translocator-like

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of ARNTL

The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene.

Community Annotation of ARNTL Add / Edit ARNTL: Annotations

No community annotations yet for ARNTL.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ARNTL is highly significantly mutated in
(none)
ARNTL is significantly mutated in
(none)
ARNTL is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ARNTL