ARMCX3 Back

armadillo repeat containing, X-linked 3

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NCBI Description of ARMCX3

This gene encodes a member of the ALEX family of proteins which may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and a single Armadillo (arm) repeat. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members on the X chromosome. Three transcript variants encoding the same protein have been identified for this gene.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ARMCX3 is highly significantly mutated in
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ARMCX3 is significantly mutated in
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ARMCX3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ARMCX3