ARMCX2 Back

armadillo repeat containing, X-linked 2

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NCBI Description of ARMCX2
This gene encodes a member of the ALEX family of proteins and may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and a single Armadillo (arm) repeat. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members, including ALEX1 and ALEX3, on the X chromosome. Two alternative transcripts that encode the same protein but differ in the 5' UTR have been described. Additional alternative transcripts may exist but their full length natures have not been determined. A pseudogene for this locus is located on chromosome 7.

Community Annotation of ARMCX2 Add / Edit ARMCX2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ARMCX2 is highly significantly mutated in
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ARMCX2 is significantly mutated in
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ARMCX2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ARMCX2