ARL6IP5 Back

ADP-ribosylation-like factor 6 interacting protein 5

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NCBI Description of ARL6IP5

Expression of this gene is affected by vitamin A. The encoded protein of this gene may be associated with the cytoskeleton. A similar protein in rats may play a role in the regulation of cell differentiation. The rat protein binds and inhibits the cell membrane glutamate transporter EAAC1. The expression of the rat gene is upregulated by retinoic acid, which results in a specific reduction in EAAC1-mediated glutamate transport.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ARL6IP5 is highly significantly mutated in
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ARL6IP5 is significantly mutated in
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ARL6IP5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ARL6IP5