ARL5A Back

ADP-ribosylation factor-like 5A

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NCBI Description of ARL5A

The protein encoded by this gene belongs to the ARF family of GTP-binding proteins. With its distinctive nuclear/nucleolar localization and interaction with HP1alpha, the protein is developmentally regulated and may play a role(s) in nuclear dynamics and/or signaling cascades during embryonic development. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene has multiple pseudogenes.

Community Annotation of ARL5A Add / Edit ARL5A: Annotations

No community annotations yet for ARL5A.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ARL5A is highly significantly mutated in
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ARL5A is significantly mutated in
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ARL5A is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ARL5A