ARHGEF19 Back

Rho guanine nucleotide exchange factor (GEF) 19

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NCBI Description of ARHGEF19
Guanine nucleotide exchange factors (GEFs) such as ARHGEF19 accelerate the GTPase activity of Rho GTPases (see RHOA, MIM 165390).[supplied by OMIM, Dec 2008]. Sequence Note: removed 1 base from the 3' end that did not align to the reference genome assembly.

Community Annotation of ARHGEF19 Add / Edit ARHGEF19: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ARHGEF19 is highly significantly mutated in
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ARHGEF19 is significantly mutated in
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ARHGEF19 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ARHGEF19