ARHGEF10 Back

Rho guanine nucleotide exchange factor (GEF) 10

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NCBI Description of ARHGEF10
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals.

Community Annotation of ARHGEF10 Add / Edit ARHGEF10: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ARHGEF10 is highly significantly mutated in
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ARHGEF10 is significantly mutated in
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ARHGEF10 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ARHGEF10