ARHGAP5 Back

Rho GTPase activating protein 5

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NCBI Description of ARHGAP5
Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene.

Community Annotation of ARHGAP5 Add / Edit ARHGAP5: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ARHGAP5 is highly significantly mutated in
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ARHGAP5 is significantly mutated in
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ARHGAP5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ARHGAP5