AQP4 Back

aquaporin 4

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NCBI Description of AQP4

This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The encoded protein is the predominant aquaporin found in brain. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Community Annotation of AQP4 Add / Edit AQP4: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

AQP4 is highly significantly mutated in
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AQP4 is significantly mutated in
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AQP4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for AQP4